Three classes of gynecological infection show up in pregnancy:
- Toxic shock syndrome (TSS). A rare, potentially fatal disorder from toxin-producing strains of Staphylococcus aureus. The toxins cause shock, coagulation defects, and tissue damage if they reach the bloodstream. It is tied to bacteria trapped in the reproductive tract too long.
- Sexually transmitted infections (STI). Spread mainly by sexual contact, though several have other routes. Human papillomavirus is the most common viral STI, with more than 100 variants.
- Pelvic inflammatory disease (PID). Infection of the upper reproductive tract, often from asymptomatic STIs. It involves the cervix, uterine cavity, fallopian tubes, and pelvic cavity, and can end in infertility.
Nursing Care Plans and Management
Care focuses on screening and identifying infection, delivering protocol-based care, and protecting maternal and fetal wellbeing.
Nursing Problem Priorities
- Identify and diagnose the infection promptly through appropriate testing.
- Assess maternal health, including vital signs and any signs of infection.
- Monitor fetal wellbeing with ultrasound, nonstress tests, or other methods.
- Give appropriate antibiotic therapy, weighing infection type and drug safety in pregnancy.
- Prevent mother-to-fetus transmission through hygiene, safe sex, and avoiding known exposures.
- Educate and support the mother on risks and treatment adherence.
- Prevent complications such as preterm labor, fetal growth restriction, and birth defects.
- Provide postpartum care and followup for both mother and baby.
Nursing Assessment
Assess for the following subjective and objective data:
- See nursing assessment cues under Nursing Interventions and Actions.
Nursing Diagnosis
Form nursing diagnoses from your assessment and clinical judgment, prioritizing each client's specific infection risks and needs.
Nursing Goals
Goals and expected outcomes may include:
- The client verbalizes individual causative and risk factors.
- The client adopts techniques and lifestyle changes to reduce infection risk and limit spread, and achieves timely healing free of complications.
- The client uses comfort measures and relaxation skills and reports discomfort relieved or controlled.
- The client provides necessary information for data collection, follows the treatment regimen, and lists signs and symptoms that need evaluation.
- The infant shows organized behaviors supporting growth and development, and the parents read the infant's stress cues and adapt their responses.
- The client views self as a worthwhile person and sets realistic goals with self-confidence.
Nursing Interventions and Actions
1. Preventing Infections
Bacterial infection is the single most common medical complication in pregnancy. Some, like puerperal endometritis and lower UTI, threaten the mother but spare the fetus. Others, like listeriosis and group B streptococcal (GBS) infection, threaten the fetus most. Still others, like pyelonephritis, chorioamnionitis, and syphilis, can be life-threatening for both.
Ask about past and present sexual partners and exposure to STIs. Multiple partners or intercourse with bisexual men raises exposure to STIs and HIV/AIDS. Include any contact with intravenous drug users.
Ask about cultural background for risk factors. In Africa the male-to-female HIV ratio is 1:1; recent arrivals from Asia, South America, and the Caribbean carry higher hepatitis B exposure.
Review lifestyle and profession for risk factors. Drug users and healthcare workers risk HIV/AIDS and HBV through contaminated needles, body fluids, and blood products, and tuberculosis through airborne droplets. Adolescents account for nearly half of new STI cases each year; watch the ones without strong family support, who have the hardest time getting accurate prevention information.
Assess for specific signs and symptoms and notify the provider: visible lesions or warts, urinary frequency, dysuria, cloudy or foul-smelling urine, and changes in vaginal discharge. Some organisms hit the fetoplacental unit while the mother is asymptomatic. Mycoplasma and Ureaplasma affect many pregnant women and have been cultured in aborted fetuses despite no maternal symptoms. Visible lesions or warts may signal HSV II/condyloma, transmissible to the newborn at delivery if a lesion is present at term or shedding is occurring. UTI symptoms may point to Escherichia coli, GBS, or asymptomatic bacteriuria. Abnormal discharge may indicate an STI.
Determine whether the infection is primary or recurrent. CMV and herpes simplex virus II (HSV-II) both recur under stress. Only primary CMV threatens the fetus, and only 50% of exposed fetuses are affected. Recurrent HSV-II has reduced shedding, but a newborn exposed at delivery can develop visible lesions or disseminated, often fatal disease.
Determine membrane status. If ruptured, monitor blood cell count and fetal heart rate, and note any odor to the discharge. Ascending organisms (Chlamydia, mycoplasmas, Ureaplasma urealyticum) can cause bacteremia, pneumonia, or meningitis. Chlamydial infection is linked to premature rupture of membranes, preterm labor, and postpartum endometritis; an exposed infant can develop conjunctivitis or pneumonia after birth.
Perform comprehensive STI and HIV screening. STIs are biological markers of HIV risk, and screening is underused. Anyone seeking evaluation for one STI should be screened for HIV and others based on community prevalence and individual risk, and told which tests they are getting.
Screen for HIV at the first prenatal visit and again in the third trimester. Test all pregnant women at the first visit. Repeat before <36 weeks gestation for women at high risk, those in jurisdictions with high HIV rates, or in settings where HIV incidence is ≥1 per 1,000 women screened per year.
Teach proper use of tampons, diaphragms, and cervical caps. To prevent toxic shock syndrome, wash hands well before insertion. Change tampons every 4 hours and don't wear them during sleep, which usually runs longer. Don't use a diaphragm during menstruation or for 8 weeks after childbirth.
Teach how to prevent STIs. Abstinence or condoms give the best protection. Void and wash the genitals with soap and water after intercourse, and choose low-risk partners. Teaching adolescents about condoms and screening is a core nursing responsibility.
Explain vaccines against STIs. Raise immunization sensitively; some clients, especially teens with a parent present, aren't ready to admit they are or will soon be sexually active. HPV immunization lowers future HPV infection and rates of cervical and penile cancer. Hepatitis B vaccine prevents the disease, and immunoglobulin can be given after known exposure.
Advise against douching. Douching alters vaginal flora and predisposes to PID, bacterial vaginosis, and ectopic pregnancy. Many women douche believing it cleanses; correct this.
Teach how to prevent toxoplasmosis. A healthy cat can stay in the home, but don't take in a new one during pregnancy. Avoid undercooked meat, don't change the litter box or garden in soil where cats defecate, and wash hands after handling raw meat.
Offer STI and HIV prevention counseling. Counseling works best when nonjudgmental and matched to the client's culture, language, gender identity, sexual orientation, age, and developmental level. Offer it to all sexually active adolescents and any adult with a current or prior-year STI or multiple partners. Client-centered counseling tailors risk reduction to the person's situation.
Obtain specimens and monitor lab and diagnostic studies as indicated. Candidal infection is diagnosed by placing discharge on a slide with hydroxide solution; fungal hyphae confirm Candida. Most STIs are diagnosed by microscopic exam of vaginal discharge. Herpes is confirmed by culture of lesion secretions or isolation of HSV antibodies. Get a urine culture in vulvovaginitis to rule out gonorrhea.
Assist with sputum collection and chest x-rays for respiratory symptoms. These identify organisms in bacterial pneumonia and active tuberculosis. Screen for TB early; it raises miscarriage risk, and as the growing uterus presses on the lungs it can reactivate healed lesions.
Give antibiotics and other medications to the client and her partner as ordered. STI treatment may include azithromycin, doxycycline, erythromycin, ceftriaxone, and benzathine penicillin G; antivirals such as acyclovir; and antifungals such as miconazole, clotrimazole, or fluconazole. Metronidazole or tinidazole treats trichomonas and Gardnerella infection and bacterial vaginosis.
Prepare for transfer to a tertiary care center as indicated. Specialized staff and equipment optimize care of high-risk clients and newborns. Toxic shock syndrome treatment includes hospitalization for vasopressors and fluid replacement.
Prepare to assist with procedures to remove lesions or warts. HPV treatment includes cryotherapy, laser vaporization, electrodiathermy, and electrofulguration with a loop electrode excision procedure. With cryocautery, edema appears immediately, lesions turn gangrenous and slough in 7 days, and healing finishes in 4 to 6 weeks with only slight depigmentation.
Prepare for termination of pregnancy or labor induction as indicated. Pregnancy may be terminated for toxoplasmosis before 20 weeks gestation or rubella in the first trimester. An infant exposed to cytomegalovirus or toxoplasmosis may be born with congenital anomalies from viral invasion.
2. Managing Acute Pain
Genital herpes can cause painful perineal or vaginal lesions, often found on history during prenatal visits, and HSV ulcers make urination painful. Chlamydia and trichomoniasis can cause painful urination, lower abdominal pain, and pain during intercourse. Manage this discomfort effectively.
Identify the source, location, and extent of discomfort and note signs of an infectious process. Vulvar or vaginal itching is typical of candidiasis and trichomoniasis. Clusters of painful vesicles on the vulva, perineum, and anus point to HSV, often with flu-like symptoms and fever. The pain is intense against clothing or acidic urine.
Take a thorough history and screen for other causes of pain. Rule out a broad differential; with a primary STI complaint, distinguish localized from systemic infection.
Teach hygiene measures for vaginal discharge from chlamydial infection or gonorrhea: frequent bathing, cotton underwear, cornstarch. A warm bath 3 times a day eases discomfort, though the moisture can prolong the active lesion phase. Avoid bubble baths and scented vaginal products. Cornstarch may cut itch and friction but has little proven benefit and can worsen irritation or feed yeast. Use cotton, not synthetics.
For HSV-II, advise warm sitz baths, drying the genital area with a hair dryer, voiding through an empty toilet paper tube, and loose clothing with cotton underwear. These keep urine off the lesions and the area dry and clean. Loose clothing reduces lesion pain.
For UTI, encourage oral fluids and voiding in a warm sitz bath. These prevent stasis; warmth relaxes the perineum and meatus to ease voiding and soothes sore tissue. Higher fluid intake dilutes contaminating bacteria and flushes them from the urinary tract.
For respiratory infection such as tuberculosis, increase fluids and use semi-Fowler's during sleep. Fluids liquefy secretions; an upright position lets the diaphragm descend and expands the lungs. Chest physiotherapy helps but is hard late in pregnancy, so plan shorter, more frequent sessions.
Encourage rest with tuberculosis or flu-like symptoms from listeriosis, rubella, or toxoplasmosis. Rest lowers metabolic rate and supports the immune response. HSV can cause systemic flu-like illness, primary CMV brings fatigue and lymphadenopathy, and arthralgias suggest rubella.
Give analgesics, antipyretics, antibiotics, and antifungals as ordered. Analgesics relieve backache, neuralgia, cervical lymphadenopathy, and perineal lesions; antipyretics control fever and chills. In PROM, avoid antipyretic analgesics like acetaminophen, which can mask a temperature rise that signals infection. Antibiotics clear UTI, bacterial pneumonia, STIs (gonorrhea, syphilis, chlamydia), and listeriosis.
Apply topical medications to the affected area. Topical antivirals reduce lesions and are mainly used for oral HSV; percutaneous absorption is poor, so they treat genital HSV-II less effectively. Penciclovir is a topical treatment for oral herpes and herpes labialis.
3. Initiating Patient Education and Health Teachings
STIs are linked to abortion, stillbirth, preterm delivery, low birth weight, postpartum sepsis, neonatal pneumonia, neonatal blindness, and congenital infection. An educated woman is better positioned to negotiate safe sex and make informed decisions.
Identify signs and symptoms of infection and stress prompt reporting. Maternal infection may be mild but serious for the fetus; timely intervention prevents complications. Syphilis, gonorrhea, chlamydia, chancroid, and HIV are reportable in every state, which supports partner notification and treatment.
Identify lifestyle risk factors. Injection drug users risk percutaneous HSV-II, HBV, HIV/AIDS, and other STIs. Multiple partners raise risk. Most US malaria occurs in travelers to endemic areas. Toxoplasmosis spreads through uncooked meat and cat stool in soil or litter.
Assess the client's knowledge, risk perception, and education level. Low education tracks with poor STI awareness. Young people are the most vulnerable and often the least informed; many pregnant clients know HIV/AIDS but no other STIs. Knowledge shapes accurate risk perception, so teach beyond HIV and fill the gaps you find.
Take a sexual history per CDC guidance. Routinely obtain sexual histories and address risk reduction. Respect, compassion, and a nonjudgmental attitude get you a thorough history and let prevention messages land.
Protect privacy and confidentiality. Tell the client STI and HIV reports are confidential and protected by statute in most jurisdictions. Before any followup on a positive result, consult her provider to verify the diagnosis and treatment and plan the approach.
Explain occupational risks and stress gloves and handwashing when handling blood, saliva, or urine. Dialysis and healthcare workers risk HSV-II, HIV, and HBV; use universal precautions and barriers, handle and dispose of sharps carefully in a sharps container, and wash skin immediately after contact.
Introduce technology-based sexuality education. eHealth, mHealth, and text- or web-based tools reach broadly at low cost, with better privacy and comfort for teens and room to tailor messages.
Discuss the mode of transmission of specific infections. This guides lifestyle changes and reinforces partner treatment. STIs spread mainly through vaginal, anal, and oral sex, but some spread through blood or blood products and from mother to child during pregnancy and birth.
Stress avoiding contact with people who have upper respiratory infection, tuberculosis, rubella (if not immune), or hepatitis, and immunizing for rubella after delivery. 5% to 15% of women of childbearing age are still susceptible to rubella, which is spread by droplets. Postpartum immunization protects future pregnancies. When exposure risk is high, hepatitis A and B, inactivated influenza, and inactivated polio vaccines are allowed in pregnancy.
Explain the possible effects of infection on the client and fetus. Infection affects about 15% of pregnancies. Rubella outcomes are fairly predictable if exposure gestational age is known; Ureaplasma, Mycoplasma, and Listeria are harder to predict, especially when the client is asymptomatic. Most infections spare the mother but vary in fetal effect. Two-thirds of exposed infants are infected in utero, with effects on the liver and brain. Ascending infections raise the chance of neonatal bacteremia and pneumonia.
Recommend gloves while gardening, avoiding cat litter, and cooking meat to safe internal temperatures. This prevents toxoplasmosis, acquired in the US mainly through cat feces and raw or undercooked meat. Wash hands after handling raw meat.
Encourage 6 to 8 glasses of fluid daily and regular voiding; discuss urine test results. This helps prevent UTI from stasis. Asymptomatic bacteriuria (colony count over 100,000/mL) raises the risk of premature delivery, congenital defects, and anemia. UTI occurs in 5% to 10% of pregnant clients, and E. coli is one of the most common culprits.
Suggest voiding after intercourse. This may reduce UTI and transmission of STIs, especially CMV and nongonococcal urethritis. Voiding within 15 minutes offers some protection for women without prior UTIs.
Suggest alternative means of sexual gratification for active HSV-II, HIV/AIDS, or HBV. Fondling or masturbation prevents spread to partners while preserving an important part of quality of life.
Discuss teratogenic treatments: sulfadiazine and pyrimethamine for toxoplasmosis, oral sulfonamides for UTI in late gestation. These have known teratogenic effects. In toxoplasmosis, the fetus can be harmed by the disease or the treatment. Oral sulfonamides can cause neonatal hyperbilirubinemia and kernicterus. Check a drug's pregnancy safety information before giving it. The old FDA five-letter category system (A, B, C, D, X) was replaced in 2015 by the Pregnancy and Lactation Labeling Rule, which gives a narrative summary of pregnancy, lactation, and reproductive risk in place of a single letter.
Discuss how infection affects the type and timing of delivery. Operative delivery may be needed for HSV-II when the client has active herpes with intact membranes, or when membranes have been ruptured more than 4 to 6 hours. An ascending infection after PROM may require preterm delivery to prevent maternal and fetal sepsis.
Explain PROM implications for client and fetus. Membrane rupture more than 18 hours before delivery raises ascending infection risk, with chorioamnionitis and maternal/neonatal sepsis. Common organisms are GBS, Chlamydiae, and Haemophilus influenzae. Treatment weighs early delivery against infection risk. Vaginal or cervical infection can itself rupture membranes early.
Review options with known teratogenic effects. The fetus is most susceptible to rubella early in gestation; HBV poses more third-trimester risk. Toxoplasmosis can cause growth retardation, CNS calcification, microcephaly, hydrocephaly, and chorioretinitis. With rubella or toxoplasmosis, the client or couple may elect termination depending on gestation.
Discuss teratogenic infections and early detection. These viral, bacterial, or protozoan organisms cross the placenta. Most cause mild flu-like symptoms in the mother but serious fetal effects. Newborn antibody testing for the common teratogenic infections is grouped under TORCH: toxoplasmosis, rubella, cytomegalovirus, and herpes simplex virus. Subclinical disease makes any fetal effect hard to predict.
Give supplemental pyridoxine (vitamin B6) and calcium as ordered. Pyridoxine prevents peripheral neuropathy when INH treats active tuberculosis. A woman with prior TB must keep calcium adequate so calcified lung pockets don't break down and reactivate disease.
Explain long-term effects and incubation periods specific to the infection. 8% to 10% of infants with congenital CMV, symptomatic or not, show neurodevelopmental abnormalities. Between 25% and 70% of newborns surviving generalized herpes infection have permanent central nervous system sequelae.
Discuss newborn care and followup for infants of HBV-active or carrier mothers. Bathe the newborn right after delivery and give HBIG and hepatitis B vaccine to prevent transmission. Follow up with hepatitis B vaccine at 1 and 6 months. Acute hepatitis B treatment is supportive; about 10% of children develop chronic hepatitis B.
Identify self-help groups and community support; refer to an STI counselor. This helps clients gather information and resolve issues. STD-program counseling reaches people with high individual risk; tailored, personalized counseling works best paired with practical condom skills.
Assess for maternal infections linked to long-term fetal complications. Schizophrenia risk rises with maternal measles, rubella, varicella-zoster, polio, herpes simplex virus type 2, bacterial pneumonia and other respiratory infections, pyelonephritis, toxoplasmosis, and genital or reproductive infections.
Note gestational age at the time of maternal infection. The second trimester is the critical window for influenza and other viral exposure tied to schizophrenia; rubella's strongest link is first-trimester exposure.
Assess the fetus or infant for effects of maternal infection. A chlamydial infection present at birth can cause neonatal conjunctivitis or pneumonia. Active herpes lesions at birth can cause severe, often fatal systemic infection. Gonorrhea at birth can cause a severe eye infection leading to blindness (ophthalmia neonatorum). Congenital syphilis shows a copper-colored rash over the face, soles, and palms, often with severe rhinitis.
Engage the client and partner about transmission risk and fetal damage. When infection is suspected, involve the client in decisions; many want a partner or support person present. Give clear information on transmission risk and potential fetal damage, and if fetal infection is confirmed, outline acceptable next steps.
Explain diagnostic procedures to evaluate the fetus. A positive PCR or virus culture from amniotic fluid confirms fetal infection; a negative result is reassuring but not definitive. Cordocentesis can quantify CMV in fetal blood and measure fetal platelet count and antibody response.
Include parents in the newborn's developmental care. Developmental care raises weight gain and cuts crying and apnea spells in preterm infants. Make parents welcome in the NICU, leave room for rocking chairs by incubators, involve them in feeding or nonnutritive sucking, and keep them informed about progress and the rationale for therapies.
Provide a safe, quiet environment for the newborn. The intensive care unit is nothing like the uterus; keep the environment as atraumatic as possible while the infant adjusts.
Reduce environmental stimuli. Dim the lights, cover the incubator, nest the infant on its side with rolled towels, offer nonnutritive sucking, and keep a quiet hour to limit sound.
Irrigate the eyes of an infant with ophthalmia neonatorum. Use sterile saline lavage to clear the copious discharge. Use a sterile dropper or bulb syringe and barrier protection, keep the solution at room temperature, and direct the stream laterally so it doesn't enter and contaminate the other eye.
Give antibiotics or antivirals to the newborn as prescribed. A newborn with signs of GBS infection or a positive screen gets penicillin, cefazolin, clindamycin, or vancomycin. Prophylactic erythromycin eye ointment prevents gonococcal and chlamydial conjunctivitis. Acyclovir treats HSV type 2; antenatal antiviral prophylaxis cuts shedding, recurrence at birth, and the need for cesarean.
Give parents information about elective procedures for the severely compromised fetus. Options are limited to termination and treatments of unproven efficacy and potential risk, such as antivirals or CMV immunoglobulin. After full risk-benefit information, let the parents decide what they think is best for their baby.
Assess the client's self-perception. Internalized stigma is accepting society's negative view of oneself, breeding shame, guilt, blame, and hopelessness. An HIV-positive client may identify with that devalued construction.
Assess economic and educational background. Lower education tracks with more personalized and disclosure stigma and self-deprecation, often tied to poorer living and working conditions and less knowledge of risk-reducing behavior.
Identify the client's strengths and past positive coping. Social support, optimism, and adaptive coping diminish the psychosocial impact of HIV. Building active coping, self-esteem, and disclosure helps pregnant women cope with an HIV-positive status.
Build a trusting relationship. Good outcomes in HIV and STI care depend on trust and engagement. Internalized shame and stigma limit access, and clients report stigma and discrimination from nurses around STI testing, which only reinforces it.
Encourage the client to express feelings and concerns. This restores a sense of control; verbalization lowers anxiety and depression and supports positive coping.
Avoid moral judgments about lifestyle. The client may already feel angry or self-condemning; outside judgment further damages self-esteem. Clients describe friendly nurses as those who let them ask questions without judgment.
Provide counseling and support to promote treatment adherence. Supportive nursing builds trust through testing and treatment. Counseling at diagnosis reduces stress, builds confidence and disclosure skills, and helps clients understand that adherence will cure the infection.
Identify and promote a support partner through pregnancy, treatment, and the postpartum period. No partner involvement is linked to more HIV stigma. Male involvement in preventing mother-to-child transmission boosts health-seeking behavior, antiretroviral adherence, appointment-keeping, and stigma mitigation.
Open a space to discuss sexuality concerns. This surfaces beliefs, values, and myths that interfere with adjustment. Female HIV and STI vulnerability is tied to gender-based power imbalances, so relational dynamics with a male partner shape risk.
Refer to structured support groups as indicated. These improve adaptive coping, self-esteem, and HIV disclosure in pregnant clients, with gains accelerating from baseline to the first followup.
Frequently Asked Questions
Why are prenatal infections dangerous when the mother feels fine? Many prenatal infections are asymptomatic in the mother while the real threat is to the fetus. Organisms can reach the fetoplacental unit without maternal symptoms, so screening at prenatal visits, identifying high-risk behavior, and counseling without judgment are how infections get caught in time to protect the baby.
What is TORCH screening? TORCH groups the common infections that cross the placenta and can cause congenital disease: toxoplasmosis, rubella, cytomegalovirus, and herpes simplex virus (the "O" sometimes covers other agents such as syphilis). Most cause mild flu-like symptoms in the mother but serious fetal effects, and subclinical disease makes the fetal impact hard to predict.
When are pregnant patients screened for group B strep? All pregnant patients are screened for GBS at 36 0/7 to 37 6/7 weeks of gestation, unless intrapartum prophylaxis is already indicated by GBS bacteriuria this pregnancy or a prior GBS-infected newborn (ACOG). Intrapartum IV penicillin G is the agent of choice to prevent early-onset neonatal GBS disease.
When should a pregnant patient be tested for HIV? The CDC recommends testing all pregnant patients at the first prenatal visit, with a second test in the third trimester (preferably before 36 weeks) for those at high risk, those in high-prevalence jurisdictions, or in settings where screening identifies at least 1 case per 1,000 pregnant patients. Early identification allows treatment that sharply lowers mother-to-child transmission.
How can pregnant patients prevent toxoplasmosis? Avoid undercooked meat, wash hands after handling raw meat, do not change the cat litter box or garden in soil where cats defecate, and do not bring a new cat into the home during pregnancy. A healthy resident cat can stay. Toxoplasmosis is acquired in the US mainly through cat feces and raw or undercooked meat.
What does prolonged rupture of membranes mean for infection risk? Rupture more than 18 hours before delivery raises the risk of ascending infection, chorioamnionitis, and maternal or neonatal sepsis, with GBS, Chlamydia, and Haemophilus influenzae among the common organisms. After rupture, monitor the white cell count and fetal heart rate, note any odor to the discharge, and avoid masking a fever with antipyretics, because management balances the risks of early delivery against infection.